D68.61

Antiphospholipid syndrome

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC ESRD V24

HCC48

Coagulation Defects and Other Specified Hematological Disorders

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

This code · D68.61

Excludes 1

anti-phospholipid antibody, finding without diagnosis (R76.0)

Excludes 2

anti-phospholipid antibody with hemorrhagic disorder (D68.312) lupus anticoagulant syndrome (D68.62)

Synonyms

Anticardiolipin syndrome Antiphospholipid antibody syndrome

Inherited from D68.6Other thrombophilia

Excludes 1

diffuse or disseminated intravascular coagulation [DIC] (D65) heparin induced thrombocytopenia (HIT) (D75.82-) hyperhomocysteinemia (E72.11)

Synonyms

Other hypercoagulable states

Inherited from D68Other coagulation defects

Excludes 1

abnormal coagulation profile NOS (R79.1)

Excludes 2

coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

Inherited from chapter 3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Excludes 2

autoimmune disease (systemic) NOS (M35.9) certain conditions originating in the perinatal period (P00-P96) complications of pregnancy, childbirth and the puerperium (O00-O9A) congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) endocrine, nutritional and metabolic diseases (E00-E88) human immunodeficiency virus [HIV] disease (B20) injury, poisoning and certain other consequences of external causes (S00-T88) neoplasms (C00-D49) symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Official Guidelines for D68.61

FY 2026 ›

I.C.3Chapter-specific guidanceChapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

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