E72.21

Argininemia

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC ESRD V24

HCC23

Other Significant Endocrine and Metabolic Disorders

RxHCC V08

RXHCC43

Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

Inherited from E72.2Disorders of urea cycle metabolism

Excludes 1

disorders of ornithine metabolism (E72.4)

Inherited from E72Other disorders of amino-acid metabolism

Excludes 1

disorders of: aromatic amino-acid metabolism (E70.-) branched-chain amino-acid metabolism (E71.0-E71.2) fatty-acid metabolism (E71.3) purine and pyrimidine metabolism (E79.-) gout (M1A.-, M10.-)

Inherited from E70-E88Metabolic disorders

Excludes 1

androgen insensitivity syndrome (E34.5-) congenital adrenal hyperplasia (E25.0) hemolytic anemias attributable to enzyme disorders (D55.-) Marfan syndrome (Q87.4-) 5-alpha-reductase deficiency (E29.1)

Excludes 2

Ehlers-Danlos syndromes (Q79.6-)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases

Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Official Guidelines for E72.21

FY 2026 ›

I.C.4Chapter-specific guidanceChapter 4: Endocrine, Nutritional, and Metabolic Diseases (E00-E89)

Subsections

Find E72.21 in the alphabetic index

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