E85.4

Organ-limited amyloidosis

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC V28

HCC50

Amyloidosis, Porphyria, and Other Specified Metabolic Disorders

CMS-HCC ESRD V24

HCC23

Other Significant Endocrine and Metabolic Disorders

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

This code · E85.4
Synonyms

Localized amyloidosis Transthyretin-related (ATTR) familial amyloid cardiomyopathy

Inherited from E85Amyloidosis
Excludes 2

Alzheimer's disease (G30.0-)

Inherited from E70-E88Metabolic disorders
Excludes 1

androgen insensitivity syndrome (E34.5-) congenital adrenal hyperplasia (E25.0) hemolytic anemias attributable to enzyme disorders (D55.-) Marfan syndrome (Q87.4-) 5-alpha-reductase deficiency (E29.1)

Excludes 2

Ehlers-Danlos syndromes (Q79.6-)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases
Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Official Guidelines for E85.4

FY 2026 ›
I.C.4Chapter-specific guidanceChapter 4: Endocrine, Nutritional, and Metabolic Diseases (E00-E89)

Subsections

Find E85.4 in the alphabetic index

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