E88.12

Generalized lipodystrophy

Billable code

This code does not map to a risk-adjusting HCC in the loaded models.

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

This code · E88.12

Synonyms

Acquired generalized lipodystrophy (AGL) Berardinelli-Siep syndrome Congenital generalized lipodystrophy (CGL) Lawrence syndrome

Inherited from E88.1Lipodystrophy, not elsewhere classified

Excludes 1

Whipple's disease (K90.81)

Inherited from E88Other and unspecified metabolic disorders

Excludes 1

histiocytosis X (chronic) (C96.6)

Use additional

codes for associated conditions

Inherited from E70-E88Metabolic disorders

Excludes 1

androgen insensitivity syndrome (E34.5-) congenital adrenal hyperplasia (E25.0) hemolytic anemias attributable to enzyme disorders (D55.-) Marfan syndrome (Q87.4-) 5-alpha-reductase deficiency (E29.1)

Excludes 2

Ehlers-Danlos syndromes (Q79.6-)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases

Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Official Guidelines for E88.12

FY 2026 ›

I.C.4Chapter-specific guidanceChapter 4: Endocrine, Nutritional, and Metabolic Diseases (E00-E89)

Subsections

Sections that reference E88.12

I.C.4.bObesity
… There are other codes related to obesity in other categories of the classification, such as E88.82, Obesity due to disruption of MC4R pathway; and codes in fifth character subcategory O99.21, Obesity complicating pregnancy, …

Sections whose FY 2026 text names E88.12, its E88 category, or a range containing it — the chapter guidance above is the authoritative source.

Find E88.12 in the alphabetic index

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