E88.A

Wasting disease (syndrome) due to underlying condition

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC ESRD V24

HCC21

Protein-Calorie Malnutrition

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

This code · E88.A
Excludes 1

cachexia NOS (R64) nutritional marasmus (E41)

Excludes 2

failure to thrive (R62.51, R62.7)

Code first

underlying condition

Synonyms

Cachexia due to underlying condition

Inherited from E88Other and unspecified metabolic disorders
Excludes 1

histiocytosis X (chronic) (C96.6)

Use additional

codes for associated conditions

Inherited from E70-E88Metabolic disorders
Excludes 1

androgen insensitivity syndrome (E34.5-) congenital adrenal hyperplasia (E25.0) hemolytic anemias attributable to enzyme disorders (D55.-) Marfan syndrome (Q87.4-) 5-alpha-reductase deficiency (E29.1)

Excludes 2

Ehlers-Danlos syndromes (Q79.6-)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases
Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Note

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Official Guidelines for E88.A

FY 2026 ›

Sections that reference E88.A

Sections whose FY 2026 text names E88.A, its E88 category, or a range containing it — the chapter guidance above is the authoritative source.