F12.21
Cannabis dependence, in remission
HCC risk adjustment mapping
CMS-HCC V28
Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
CMS-HCC ESRD V24
Substance Use Disorder, Moderate/Severe, or Substance Use with Complications
Coding notes
Excludes 1 never coded together · Excludes 2 may co-exist
Cannabis use disorder, moderate, in early remission Cannabis use disorder, moderate, in sustained remission Cannabis use disorder, severe, in early remission Cannabis use disorder, severe, in sustained remission
marijuana
disorders of psychological development
symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
Official Guidelines for F12.21
FY 2026 ›Sections that reference F12.21
- I.C.5.b.3)Psychoactive Substance Use, Unspecified
As with all other unspecified diagnoses, the codes for unspecified psychoactive substance use (F10.9-, F11.9-, F12.9-, F13.9-, F14.9-, F15.9-, F16.9-, F18.9-, F19.9-) should only be assigned based on provider documentation and when they meet …
- I.C.5.b.1)In Remission
Selection of codes describing “in remission” for categories F10-F19, Mental and behavioral disorders due to psychoactive substance use (categories F10-F19 with -.11, -.21, -.91) requires the …
- I.C.15.l.3)Drug use during pregnancy, childbirth and the puerperiumChapter 15
… Secondary code(s) from categories F11-F16 and F18-F19 should also be assigned to identify manifestations of the drug use.
Sections whose FY 2026 text names F12.21, its F12 category, or a range containing it — the chapter guidance above is the authoritative source.
Find F12.21 in the alphabetic index
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