F16.921
Hallucinogen use, unspecified with intoxication with delirium
HCC risk adjustment mapping
CMS-HCC V28
Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
CMS-HCC ESRD V24
Substance Use Disorder, Moderate/Severe, or Substance Use with Complications
Coding notes
Excludes 1 never coded together · Excludes 2 may co-exist
Other hallucinogen intoxication delirium
ecstasy PCP phencyclidine
disorders of psychological development
symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
Official Guidelines for F16.921
FY 2026 ›Sections that reference F16.921
- I.C.5.b.3)Psychoactive Substance Use, Unspecified
… unspecified diagnoses, the codes for unspecified psychoactive substance use (F10.9-, F11.9-, F12.9-, F13.9-, F14.9-, F15.9-, F16.9-, F18.9-, F19.9-) should only be assigned based on provider documentation and when they meet the definition of a reportable …
- I.C.5.b.1)In Remission
Selection of codes describing “in remission” for categories F10-F19, Mental and behavioral disorders due to psychoactive substance use (categories F10-F19 with -.11, -.21, -.91) requires the …
- I.C.15.l.3)Drug use during pregnancy, childbirth and the puerperiumChapter 15
… Secondary code(s) from categories F11-F16 and F18-F19 should also be assigned to identify manifestations of the drug use.
Sections whose FY 2026 text names F16.921, its F16 category, or a range containing it — the chapter guidance above is the authoritative source.
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