F19.27
Other psychoactive substance dependence with psychoactive substance-induced persisting dementia
HCC risk adjustment mapping
CMS-HCC V28
Drug Use with Psychotic Complications
CMS-HCC ESRD V24
Substance Use with Psychotic Complications
Coding notes
Excludes 1 never coded together · Excludes 2 may co-exist
Other (or unknown) substance use disorder, moderate, with other (or unknown) substance induced major neurocognitive disorder Other (or unknown) substance use disorder, severe, with other (or unknown) substance induced major neurocognitive disorder
polysubstance drug use (indiscriminate drug use)
disorders of psychological development
symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
Official Guidelines for F19.27
FY 2026 ›Sections that reference F19.27
- I.C.5.b.3)Psychoactive Substance Use, Unspecified
… the codes for unspecified psychoactive substance use (F10.9-, F11.9-, F12.9-, F13.9-, F14.9-, F15.9-, F16.9-, F18.9-, F19.9-) should only be assigned based on provider documentation and when they meet the definition of a reportable diagnosis (see …
- I.C.5.b.1)In Remission
Selection of codes describing “in remission” for categories F10-F19, Mental and behavioral disorders due to psychoactive substance use (categories F10-F19 with -.11, -.21, -.91) requires the …
- I.C.15.l.3)Drug use during pregnancy, childbirth and the puerperiumChapter 15
… Secondary code(s) from categories F11-F16 and F18-F19 should also be assigned to identify manifestations of the drug use.
Sections whose FY 2026 text names F19.27, its F19 category, or a range containing it — the chapter guidance above is the authoritative source.
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