J45.51

Severe persistent asthma with (acute) exacerbation

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC V28

HCC279

Severe Persistent Asthma

RxHCC V08

RXHCC228

Severe Persistent Asthma

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

Inherited from J45Asthma
Includes

allergic (predominantly) asthma allergic bronchitis NOS allergic rhinitis with asthma atopic asthma extrinsic allergic asthma hay fever with asthma idiosyncratic asthma intrinsic nonallergic asthma nonallergic asthma

Excludes 1

detergent asthma (J69.8) miner's asthma (J60) wheezing NOS (R06.2) wood asthma (J67.8)

Excludes 2

asthma with chronic obstructive pulmonary disease (J44.89) chronic asthmatic (obstructive) bronchitis (J44.89) chronic obstructive asthma (J44.89) other specified chronic obstructive pulmonary disease (J44.89)

Use additional

code to identify: eosinophilic asthma (J82.83) exposure to environmental tobacco smoke (Z77.22) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco dependence (Z87.891) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0)

Inherited from J40-J4AChronic lower respiratory diseases
Excludes 1

bronchitis due to chemicals, gases, fumes and vapors (J68.0)

Excludes 2

cystic fibrosis (E84.-)

Inherited from chapter 10Diseases of the respiratory system
Excludes 2

certain conditions originating in the perinatal period (P04-P96) certain infectious and parasitic diseases (A00-B99) complications of pregnancy, childbirth and the puerperium (O00-O9A) congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) endocrine, nutritional and metabolic diseases (E00-E88) injury, poisoning and certain other consequences of external causes (S00-T88) neoplasms (C00-D49) smoke inhalation (T59.81-) symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use additional

code, where applicable, to identify: exposure to environmental tobacco smoke (Z77.22) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco dependence (Z87.891) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0)

Note

When a respiratory condition is described as occurring in more than one site and is not specifically indexed, it should be classified to the lower anatomic site (e.g. tracheobronchitis to bronchitis in J40).

Official Guidelines for J45.51

FY 2026 ›

Sections that reference J45.51

Sections whose FY 2026 text names J45.51, its J45 category, or a range containing it — the chapter guidance above is the authoritative source.