Z79.81
Long term (current) use of agents affecting estrogen receptors and estrogen levels
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This code does not map to a risk-adjusting HCC in the loaded models.
Coding notes
Excludes 1 never coded together · Excludes 2 may co-exist
hormone replacement therapy (Z79.890)
code, if applicable, to identify: estrogen receptor positive status (Z17.0) family history of breast cancer (Z80.3) genetic susceptibility to malignant neoplasm (cancer) (Z15.0-) personal history of breast cancer (Z85.3) personal history of prostate cancer (Z85.46) postmenopausal status (Z78.0)
any follow-up examination (Z08-Z09)
Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways: (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury. (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
Official Guidelines for Z79.81
FY 2026 ›Sections that reference Z79.81
- I.C.1.a.2)(j)HIV disease or HIV positive status managed by antiretroviral medicationChapter 1
… [HIV] infection status, in the absence of any additional documentation of HIV disease, HIV-related illness or AIDS. Code Z79.899, Other long term (current) drug therapy, may be assigned as an additional code to identify the long-term (current) use of …
- I.C.4.a.3)Diabetes mellitus and the use of insulin, oral hypoglycemics, and injectable non-insulin drugsChapter 4
… Additional code(s) should be assigned from category Z79 to identify the long-term (current) use of insulin, oral hypoglycemic drugs, or injectable non-insulin antidiabetic, as …
- I.C.4.a.6)(a)Secondary diabetes mellitus and the use of insulin, oral hypoglycemic drugs, or injectable non-insulin drugsChapter 4
… mellitus who routinely use insulin, oral hypoglycemic drugs, or injectable non-insulin drugs, additional code(s) from category Z79 should be assigned to identify the long-term (current) use of insulin, oral hypoglycemic drugs, or non-injectable non-insulin …
- I.C.15.iGestational (pregnancy induced) diabetesChapter 15
… Codes Z79.4, Long-term (current) use of insulin, Z79.84, Long-term (current) use of oral hypoglycemic drugs, and Z79.85, Long-term …
- I.C.21.c.3)Status
… code should not be reported when it is documented by the provider that a patient is temporarily restrained during a procedure. Z79 Long-term (current) drug therapy Codes from this category indicate a patient’s continuous use of a prescribed drug (including …
- I.B.3Code or codes from A00.0 through T88.9, Z00-Z99.8, U00-U85Conventions & general rules
The appropriate code or codes from A00.0 through T88.9, Z00-Z99.8, and U00-U85 must be used to identify diagnoses, symptoms, conditions, problems, complaints or other reason(s) for the …
Showing 6 of 9. Search the guidelines for Z79. Sections whose FY 2026 text names Z79.81, its Z79 category, or a range containing it — the chapter guidance above is the authoritative source.