I.C.5.b.2)

Psychoactive Substance Use, Abuse and Dependence

When the provider documentation refers to use, abuse and dependence of the same substance (e.g. alcohol, opioid, cannabis, etc.), only one code should be assigned to identify the pattern of use based on the following hierarchy: • If both use and abuse are documented, assign only the code for abuse • If both abuse and dependence are documented, assign only the code for dependence • If use, abuse and dependence are all documented, assign only the code for dependence • If both use and dependence are documented, assign only the code for dependence.

ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026 (effective October 1, 2025). Published by CMS and NCHS. Reproduced for reference — always verify against the official CMS release.