E22

Hyperfunction of pituitary gland

Header / non-billable

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This code does not map to a risk-adjusting HCC in the loaded models.

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

This code · E22
Excludes 1

Cushing's syndrome (E24.-) Nelson's syndrome (E24.1) overproduction of ACTH not associated with Cushing's disease (E27.0) overproduction of pituitary ACTH (E24.0) overproduction of thyroid-stimulating hormone (E05.8-)

Inherited from E20-E35Disorders of other endocrine glands
Excludes 1

galactorrhea (N64.3) gynecomastia (N62)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases
Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Note

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Official Guidelines for E22

FY 2026 ›
I.C.4Chapter-specific guidanceChapter 4: Endocrine, Nutritional, and Metabolic Diseases (E00-E89)

Subsections