E22.2

Syndrome of inappropriate secretion of antidiuretic hormone

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC ESRD V24

HCC23

Other Significant Endocrine and Metabolic Disorders

RxHCC V08

RXHCC43

Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

Inherited from E22Hyperfunction of pituitary gland
Excludes 1

Cushing's syndrome (E24.-) Nelson's syndrome (E24.1) overproduction of ACTH not associated with Cushing's disease (E27.0) overproduction of pituitary ACTH (E24.0) overproduction of thyroid-stimulating hormone (E05.8-)

Inherited from E20-E35Disorders of other endocrine glands
Excludes 1

galactorrhea (N64.3) gynecomastia (N62)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases
Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Official Guidelines for E22.2

FY 2026 ›