E22.9

Hyperfunction of pituitary gland, unspecified

Risk-adjusting (HCC)Billable code

HCC risk adjustment mapping

CMS-HCC ESRD V24

HCC23

Other Significant Endocrine and Metabolic Disorders

RxHCC V08

RXHCC43

Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders

Coding notes

Excludes 1 never coded together · Excludes 2 may co-exist

Inherited from E22Hyperfunction of pituitary gland
Excludes 1

Cushing's syndrome (E24.-) Nelson's syndrome (E24.1) overproduction of ACTH not associated with Cushing's disease (E27.0) overproduction of pituitary ACTH (E24.0) overproduction of thyroid-stimulating hormone (E05.8-)

Inherited from E20-E35Disorders of other endocrine glands
Excludes 1

galactorrhea (N64.3) gynecomastia (N62)

Inherited from chapter 4Endocrine, nutritional and metabolic diseases
Excludes 1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Note

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Official Guidelines for E22.9

FY 2026 ›